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PPI - Proton Pump Inhibitor Drugs

Unsafe Drugs

PPI - Proton Pump Inhibitor Drugs

PPIs are a class of drugs that decrease gastric acid secretion. This PPI class of drugs is comprised of some of the best selling drugs on the market accounting for almost a $13 billion a year industry. The most popular PPIs (proton pump inhibitors) are Prilosec, Nexium, Prevacid, Protonix, and Aciphex.

In a recent study, PPI has been associated with increased risk of hip fractures from osteoporosis. PPIs suppress the secretion of acid in the stomach which makes the stomach less acidic. A less acidic stomach may impair absorption of calcium, in particular, calcium supplements. A decrease in the absorption of calcium leads to low body calcium. Low body calcium levels make the bones weak by causing osteoporosis. Fractures are the most serious consequences of osteoporosis and hip fractures are the most common fractures in osteoporosis.

Which is worse...heartburn or osteoporosis?

According to the University of Pennsylvania study, people over age 50 who take PPI drugs for more than one year have a 44% increased risk of breaking a hip. PPIs increased risk for fracture occurred to a greater degree in men than women. Use of high-dose PPIs further increased the risk for hip fracture when compared to regular dosing. People who have taken PPI drugs for five years or longer are most at risk.

Have you or a loved one suffered a hip fracture or been diagnosed with osteoporosis because of taking PPI drugs? You may be eligible for a PPI lawsuit. For victims in PA, WV, or NJ, consider of counsel law firm Anapol Schwartz.

PPI drugs are prescribed for:

  • Gastroesophageal Reflux Disease (GERD)
  • Stress gastritis
  • Barrett's esophagus
  • Peptic ulcer disease
  • Dyspepsia

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